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Biomedical scientists from UT Southwestern Medical Center of the University of Texas and nanotechnology experts from UT Dallas describe their experiments the available research journal Proceedings of the National Academy of Sciences. Scientists are able to use biological molecules called destoner machine monoclonal antibodies that bind to cancer cells. Antibodies can work alone or drugs bind to powerful anti-cancer, radionuclides destoner machine or toxins (toxins) to transfer the deadliest substances cancer cells.
In this study, researchers used monoclonal antibodies targeted specific sites on lymphoma destoner machine cells (cancer lymph nodes) to cover tiny structures called carbon nanotubes. Carbon nanotubes are extremely small tubes of graphite exposed to the warming-infrared close. This type of light, invisible to the human eye, is used for remote control of the TV to switch channels and is detected by night-vision goggles. Light can penetrate human tissue about four inches. Cultured lymphoma cells, nano tubes coated destoner machine antibodies bind to the surface of the cells. When cells goal were then exposed to near-infrared light, the nanotubes heated up, generating enough heat to "cook" the cells and kill them. nanotubes coated destoner machine antibody neither bound tumor cells Yeah also not been able to destroy them.
"Using radiation to near-infrared light for the induction of lethal heat ((hyperthermia is particularly attractive because living tissues do not strongly absorb radiation in this range," says Dr. Ellen Vitetta, director of the Center of the Cancer Immunobiology at UT Southwestern and senior author of the paper. "Once the carbon nanotubes destoner machine have bound to the tumor cells, an external source of infrared destoner machine light can be used safely penetrate normal tissues and kill the cancer cells.
"Demonstrating this specific killing was the objective of the present study. We have worked for many years with targeted therapies and even if you can demonstrate a degree of specificity in a laboratory dish, there are still many hurdles to translating these new clinical trials. We're just beginning to test this in mice , and although there is no guarantee it will work, we are very optimistic. "
The use of carbon nanotubes to the elimination of cancer cells heat is being explored by several research groups, but the new study is the first to show that both the antibody destoner machine and the carbon nanotubes retained their physical properties and abilities - binding to and killing only the targeted cells. This was true even when the antibody-nanotube placed in a setting designed to mimic conditions inside the human body. Biomedical applications of nanoparticles are attracting increasingly the attention of scientists in clinical and basic research scientists. However, there are challenges in developing successful medical nanoscale materials. One of them is the possibility that a new nanomaterial can damage healthy cells and organisms. This requires a careful and thorough examination of the effects of nanoparticles on the human body in order to assess their toxicity. "There are rational approaches to identify and minimize nonspecific toxicity of the nanoparticles developed in our research," destoner machine says Dr. Rockford Draper, head of the team from UT Dallas and a professor destoner machine of molecular and cell biology.
I wish I could, the country we are indeed high-tech superpower field Hnnotcnologybioainformtika but there are not so many companies involved in the field. And I say this from experience I chose no choice destoner machine but to deal with computers instead of computational biology because of the country (except research universities) do not just develop ideas to it. Unfortunately. July 25th, 2008
Eli.r There is probably no such danger but if there is to be discovered in the experiment. destoner machine Of course there are other ways to solve the problem and it does not mean that there is no way to try to work with. It reminds me of a joke about in-law who was always quarreling with her groom and one day decided to make peace and reflection Lbicoa brought him two ties. The groom wanted to show enthusiasm ran straight into the next room, one grape tie in the mirror and returned destoner machine to show everyone that he has been wearing it. Straight-in-law said she saw him: "What is it? And the other did not you like?" It is. So feel free to do research that makes use of P53 and apoptosis. These researchers will continue their study and others will explore other things. He falls out interesting book "The Transformed Cell" destoner machine by Steven Rosenberg. July 24th, 2008
Creating environmental heat can destroy healthy lymph cells. There is perhaps no surer way like trying to activate destoner machine the mechanism of apoptosis of the cell, assuming we know exactly how T lymphocytes (cytokine) causes apoptosis of the cell itself, there is no way to emulate the same mechanism just say if we detect a nano molecule imitate the action of Hfrforin creation of apoptosis in place -specific environmental heating? July 24th, 2008
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