Obesity has become the most severe health problems in the world. frasers centrepoint malls WHO, World Health Organization estimates that the number of people suffering from obesity and exceeded 300 million. In the United frasers centrepoint malls States, authorities have estimated frasers centrepoint malls the proportion of (body mass index> 30) obese people of the adult population and is 27%. Is about 33% of the adult population the proportion of (body mass index 25 to 30) people frasers centrepoint malls overweight, (NCCDPHP 2003). Also, this is also a significant health problems in Finland. Adult fifth is overweight all. The number of obese people in the industrialized countries, will double in about '20, conversion of trend can not be seen (WHO 2003). The reason underlying the obesity, there is a decrease in physical activity along with the energy of a certain amount or a large amount of nutrition.
In nutrition, fat, are evaluating increasing fat because frasers centrepoint malls it has a high energy most, evolves, a person, not only as an energy source, there is a preference. In the industrialized countries of all, fat content of the nutrition is above recommendations almost. Not only damages the cosmetic which is associated with obesity, and complications serious health problem, for example, frasers centrepoint malls overdose continuous fat, causing cardiovascular disease, respiratory disease, frasers centrepoint malls diabetes was related to disease. The considerable cost, the national disease also associated. The most preferred method frasers centrepoint malls of preventing the weaknesses of excess fat, is an adjustment of the energy obtained from food and the promotion of exercise. For example, by continuing strict diet, by using low fat products energy intake, or can be reduced by preventing full use of the energy in the food.
By the target of reducing the fat content of food products, new challenges occurs in the grocery industry. I started a discussion that is open for the development of grocery future more healthy, food processing industry frasers centrepoint malls and WHO. Also experts in other tissues (eg, IASO 2003), which intensified the pressure on the industry. As a result, the food products several companies, was set as a goal to reduce the amount of product as well as improve the quality of the fat. The low-energy fat mixture, for example, are described in International Application No. O0 / 15043 discloses, the fat composition of the first of this kind have come into the market. However, in Europe, progress has been stalled by strict laws and regulations, including the licensing procedures that take years.
An efficient solution of the problem more excessive fat is to prevent be absorbed fat. For cholesterol, as a solution based on this idea, for example, can be cited as an example as described in WO 03/026672 WO application, a method based on plant stanols and plant sterols. For example, No. 5,453,282 U.S. Patent chitosan-containing nutrients for preventing the main component of the fat, the absorption of triacylglycerols (TAG) are disclosed, for some time, the most effective prevention, only by drug therapy have been successful. Prescription drugs are disclosed in EP 129 748 discloses, orlistat (tetrahydrolipstatin), (Zhi et al., 1994) that can be used to 30% by reducing the absorption of triacylglycerols. However, the problem of the use of orlistat is the fact that the disabled relative medications include, that is necessary visits to the doctor. Achieving the prevention of fat absorbed by the functional food is a very interesting solution to the problem that has been recognized internationally serious.
The present invention is based on the surprising finding of food emulsifier authorized, of preventing almost completely fat absorption from the gastrointestinal tract. The finding frasers centrepoint malls was found in clinical tests carried out for the purpose that how formulations and different treatments may find they affect the absorption of valuable fats. Therefore, as an ingredient or additive in food, health frasers centrepoint malls benefits, ie, the present invention relates to the use of an emulsifier of food approved as a pharmaceutical frasers centrepoint malls formulation or nutritional additives to achieve a complete prevention or partial of fat absorption. In this context, 'a food emulsifier approved' relates formulations approved as food additives, detergents, frasers centrepoint malls stabilizing or emulsifying agents. In the use according to the invention, emulsifiers of preferred food approved include sorbitan derivatives of formula I.
(In the formula, w + x + y + z = or about 20, w, x, y, z = 0, R is H, OOC (CH 2) 10 -CH 3, OOC (CH 2) 14 -CH 3, OOC- (CH 2) 7 - (CH) 2 -. or (CH 2) 7 -CH 3 3XOOC-) sorbitan derivative is (CH 2) 16 -CH 3, for example, sorbitan monostearate (E 491), polyoxyethylene sorbitan derivatives different (E 493), sorbitan monooleate frasers centrepoint malls (E 494), sorbitan monopalmitate or (E 495),, for example, sorbitan tristearate (E 492), sorbitan monolaurate - monolaurate (E 432), - (E 433), monooleate - (E 434), monopalmitate - (E 435), monostearate - (E 436) is particularly preferred tristearate. Sorbitan monooleate are particularly preferred emulsifiers according to the invention is (E 494).
The emulsifier of the preferred food other approved, other fatty acid derivates, for example, sucrose esters of fatty acids (E 471), mono sodium salt, calcium salt and potassium salt (E 470a), and magnesium salts (E 473) - and diglycerides (E 471), mono - acetic acid esters frasers centrepoint malls and diglycerides (E 472a), mono - lactic acid esters of diglycerides and (E 472b), mono - citric frasers centrepoint malls acid and diglycerides (E 472c) ester, mono - tartaric acid esters of diglycerides and ( E 472d), mono - mono and diglycerides - diacetyl tartaric acid esters and (E 472e), mono - a mixture of tartaric acid ester and acetic acid esters frasers centrepoint malls and diglycerides (E 472f) are included. Particularly preferred fatty acid derivative emulsifier of the present invention, sucrose frasers centrepoint malls esters of fatty acids.
The nutritional composition of the present invention is the first functional food that has been found to show an almost complete prevention of fat absorption in humans or animals. In the present invention, frasers centrepoint malls the 'functional foods', by which not only the nutritional properties of the conventional, to promote health or reducing the risk of disease for one or more functions of the organism clear effects (positive effect means the nutritional / food may have) indicated.
The functional food of the present invention may be any food emulsifiers according to the invention is added, preferred foods, liquid foods or other beverages, for example, juice, milk beverages, gruel, soups, sauces I can be mentioned. Examples of components of food or fat-containing foods may be added emulsifier food approval of the invention, for example, source fat emulsion for other use, cream imitation products, ice cream, milky, hamburger baking or meat products source, frasers centrepoint malls salad sauce, dipping sauce, heat treated, for example, hamburgers cooked chocolate include various. The functional food of the present invention, fat food, for example, pastries, cookies, potato chips, hamburgers, chocolate contains fat emulsion of the above is from using the preparation of them. Preferred frasers centrepoint malls use other forms will be apparent to those skilled frasers centrepoint malls in the art, the above examples are not intended to limit the application of the other outside the scope of the present invention.
The nutritional composition of the present invention, emulsifier amount approved food the desired frasers centrepoint malls effect as achieved are added. frasers centrepoint malls The effective amount can also, depending on the composition of the food is changed considerably with the size of the dose of the food to be ingested at a time. Also, the effective amount of the emulsifier, it can be varied according to the amount of food emulsifier used, the food is ingested. Effective amount of emulsifier, 1~25g / kg, most preferably for food (of 1kg), 0.1~100g / kg, and more preferably 5~10g / kg.
For example, preferred mode of use of the present frasers centrepoint malls invention is a functional food as 'energy drink' or snack bar, consuming separately to be ingested in addition to the standard nutrition. It is possible that by ingesting the emulsifier of the present invention as a separate supplement, effective frasers centrepoint malls prevention of fat absorption is also achieved. Supplement of the present invention,
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